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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
24.24
Human Site:
Y359
Identified Species:
35.56
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
Y359
D
P
R
I
F
Q
G
Y
S
F
V
A
P
S
I
Chimpanzee
Pan troglodytes
XP_508900
901
98668
Y488
D
P
R
I
F
Q
G
Y
S
F
V
A
P
S
I
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
Y359
D
P
R
I
F
Q
G
Y
S
F
V
A
P
S
I
Dog
Lupus familis
XP_854926
772
85603
Y359
D
P
R
I
F
Q
G
Y
S
F
V
A
P
S
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
Y359
D
P
R
I
F
Q
G
Y
S
F
V
A
P
S
I
Rat
Rattus norvegicus
Q63531
735
82865
K339
R
E
I
K
P
P
F
K
P
A
V
A
Q
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
I299
Y
S
F
V
A
P
S
I
L
F
K
R
N
A
A
Chicken
Gallus gallus
Q5F3L1
789
89022
S366
E
K
I
F
Q
G
Y
S
F
V
A
P
S
I
L
Frog
Xenopus laevis
P10665
733
82620
V342
S
P
P
F
K
P
A
V
T
Q
A
D
D
T
Y
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
F343
R
R
E
L
Q
P
P
F
K
P
A
S
G
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
D575
V
P
E
D
P
E
C
D
A
P
P
S
R
I
R
Honey Bee
Apis mellifera
XP_395099
910
102507
S398
D
K
I
F
R
G
Y
S
Y
V
A
P
S
I
L
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
E317
D
T
Q
F
F
S
A
E
F
T
S
Q
P
P
L
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
Y334
D
A
R
V
F
R
G
Y
S
F
I
A
P
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
S82
V
G
P
S
L
V
V
S
H
S
L
K
M
N
K
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
H290
I
N
T
N
Q
D
I
H
L
D
S
F
H
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
0
6.6
0
N.A.
6.6
6.6
20
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
20
13.3
20
20
N.A.
26.6
13.3
33.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
7
0
13
0
7
7
25
44
0
7
7
% A
% Cys:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% C
% Asp:
50
0
0
7
0
7
0
7
0
7
0
7
7
0
7
% D
% Glu:
7
7
13
0
0
7
0
7
0
0
0
0
0
0
0
% E
% Phe:
0
0
7
25
44
0
7
7
13
44
0
7
0
0
0
% F
% Gly:
0
7
0
0
0
13
38
0
0
0
0
0
7
0
0
% G
% His:
0
0
0
0
0
0
0
7
7
0
0
0
7
0
0
% H
% Ile:
7
0
19
32
0
0
7
7
0
0
7
0
0
19
38
% I
% Lys:
0
13
0
7
7
0
0
7
7
0
7
7
0
7
7
% K
% Leu:
0
0
0
7
7
0
0
0
13
0
7
0
0
7
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
7
0
7
0
0
0
0
0
0
0
0
7
7
0
% N
% Pro:
0
44
13
0
13
25
7
0
7
13
7
13
44
13
13
% P
% Gln:
0
0
7
0
19
32
0
0
0
7
0
7
7
0
0
% Q
% Arg:
13
7
38
0
7
7
0
0
0
0
0
7
7
0
7
% R
% Ser:
7
7
0
7
0
7
7
19
38
7
13
13
13
38
0
% S
% Thr:
0
7
7
0
0
0
0
0
7
7
0
0
0
7
0
% T
% Val:
13
0
0
13
0
7
7
7
0
13
38
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
13
38
7
0
0
0
0
0
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _